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It’s a cheaper alternative to Viagra. In Sildenafil generic tablets, there’s an ingredient called sildenafil citrate. You get it in Viagra too. It’s a type of medicine that helps to relax the blood vessels around the penis.
Erectile dysfunction happens when not enough blood can get into the penis. It’s understood to affect around half of all men aged between 40 and 70 to some extent.[1] So it’s more common than you might think (and if you do experience it, you’re definitely not alone).
The culprit is tight blood vessels, which stop blood from flowing in. An enzyme called PDE5 is what causes this.
Sildenafil counters the effects of this enzyme, so blood can reach the penis. And then, hey presto — a firmer and longer-lasting erection.
Because Sildenafil is a generic, it’s cheaper than Viagra. But it’s the same drug and shouldn’t be any less effective.
How does Sildenafil work?
Sildenafil citrate is a type of drug called a PDE5 inhibitor, which just means that it stops the PDE5 enzyme from tightening up blood vessels in your penis. This allows more blood to flow into your penis, and makes it easier for you to get a harder, longer lasting erection.
So Sildenafil looks after your physical needs. It does fall short of being an aphrodisiac though, so you’ll have to be aroused for it to work.
What Sildenafil dosage is right for me?
Sildenafil tablets come in 20mg, 25mg, 50mg and 100mg doses. So exactly the same doses as Viagra, plus one extra slightly lower dose.
If you’re taking it for the first time, you’ll normally start on Sildenafil 50mg. If you take this dose and it works well but you get mild side effects, our clinician will suggest lowering your dose to 25mg.
Starting on a 20mg 25mg dose may also be recommended if you have any risk factors which make you more prone to side effects (like diabetes for example).
Sildenafil 100mg is only for when you’ve tried 50mg and it hasn’t been strong enough. It’s the absolute maximum dose.
Treated trusted source:
Domes, T., et al (2021). Canadian Urological Association guideline: Erectile dysfunction. Canadian Urological Association Journal, 15(10).
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on August 29, 2025. Next review due on August 29, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
SildenafilSildenafil
How to take Sildenafil
Take Sildenafil one hour before you plan to have sex, and swallow your tablet whole with water. It should take no more than between half an hour and an hour to work. Never take Sildenafil more than once in any 24 hour period.
Stick to the dose prescribed for you by our clinician. If you take more Sildenafil tablets than you should, seek medical attention.
If you get any serious side effects, go to your nearest hospital as soon as possible. This includes any signs of an allergic reaction, chest pain or an erection that lasts for four hours or more and won’t go away on its own.
How long does it take for Sildenafil to work?
Clinical studies indicate Sildenafil can work in as little as 12 minutes, with the average being 30 minutes.[1] This means after taking your tablet, within 30 minutes there should be an increased blood flow to your penis, allowing you to achieve an erection.
How long does Sildenafil last?
Sildenafil remains active in the body for up to five hours. As long as you take the tablet correctly, it should give you plenty of time to have sex with your partner. If you find it doesn’t last long enough for sex though, let our clinician know, and they can discuss strengthening your dose with you.
What should I do if Sildenafil doesn’t work?
If it doesn’t work for you, get in touch with our prescriber. They’ll be able to suggest a different dose or an alternative drug. You just need to log in to your account and send our clinician a message. Adjusting your subscription plan is really easy if you want to switch to a different medication.
Treated trusted source:
Eardley, I., et al (2002). Onset and duration of action of sildenafil for the treatment of erectile dysfunction. British Journal of Clinical Pharmacology, 53(Suppl 1), 61S.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on August 29, 2025. Next review due on August 29, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
SildenafilSildenafil
Sildenafil isn’t the best choice for everyone, and there are some things that you need to be aware of when taking it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
SildenafilSildenafil
Sildenafil: FAQ
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
How effective is Sildenafil?
Answer:
For most men who take Sildenafil, it works the first or second time.
The effectiveness of Sildenafil has been reviewed in clinical studies. It helped to improve erections in:
63% of men using the 25mg dose
74% [1] of men using the 50mg dose
and 82% of men using the 100mg dose.
If you take Sildenafil but it doesn’t work as well as you’d like it to, our clinician can either help you find a more effective dose or recommend other medications for you.
Is there any difference between Viagra and Sildenafil?
Answer:
Sildenafil is a generic medication, so it’s less expensive than Viagra. Some people call Sildenafil ‘cheap Viagra’ for this reason, but it does the same thing in the body and is usually just as effective.
Viagra is a brand-name medication from Pfizer, and the tablets have a distinct blue appearance and come in a recognizable box. Sildenafil isn’t always made by Pfizer, so the appearance of Sildenafil pills can vary from one manufacturer to the next.
Some men prefer Viagra over the Sildenafil generic. But the two drugs are clinically bioequivalent, which means there’s little to no difference between them in how well they work.
Sildenafil vs Tadalafil: Which is better?
Answer:
It depends on the person taking it and what their sexual habits are. Even though they work in a similar way, the two are quite different. Tadalafil, the generic version of Cialis, is available as an on-demand weekend pill (that lasts for up to 36 hours) or a low dose every day pill.
Sildenafil is an on-demand pill that lasts for up to five hours. It’s usually a bit cheaper than Tadalafil, and for some men who don’t want to take medication every day, the five hour window for sex on Sildenafil does the trick.
Can you get Sildenafil for women?
Answer:
No. Neither Sildenafil nor drugs in the same class are appropriate or safe for women. There is a drug that’s often referred to as the ‘female Sildenafil’ called Addyi, but it’s for hypoactive sexual desire disorder (HSDD). So it’s in no way similar to any licensed erectile dysfunction drug.
Treated trusted source:
Wagner, G., et al (2001). Sildenafil Citrate (VIAGRA) Improves Erectile Function in Elderly Patients With Erectile Dysfunction: A Subgroup Analysis. Oxford Academic. The Journals of Gerontology: Series A, Volume 56, Issue 2, 1 February 2001, Pages M113–M119.
Last updated on Aug 29, 2025.
How we reviewed this page:
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Why this page was updated on Aug 29, 2025
'Content checked and updated as part of our 3-yearly periodic review, to ensure accuracy and currentness.'
Current version (Aug 29, 2025)
Edited by: The Treated Content Team.Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
Aug 01, 2022
Published by: The Treated Content Team.Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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