Xenical (orlistat) - pros and cons
Clinical trials have found that following 56 weeks of treatment participants using orlistat were found to have an eight percent weight loss, versus four percent in the placebo group. However, the clinical trials also revealed that some people experience unpleasant side effects, such as fatty stools or flatulence. As Xenical is taken orally it may be favored by users who aren’t keen on regular injections, like those used by Saxenda and Wegovy which have to be regularly injected and first demonstrated by a medical professional.
Alli – pros and cons
One of the advantages of Alli is that it is available without prescription, you will still need to speak to a pharmacist before they can provide you with the treatment, but the simpler access can be viewed as a benefit to some people. Clinical trials have proven that Alli is only marginally effective in comparison to various other weight loss pills as it is given at a lower dose. Both Xenical and Orlistat are administered in larger doses and so are often more effective at reducing weight. Alli might be more suitable for those who wish to lose a smaller amount of weight. Clinical trials have also revealed that taking Alli can result in uncomfortable side effects such as uncontrollable bowel movements, oily discharge, and gas from the anus.
Saxenda - pros and cons
The active ingredient in Saxenda, liraglutide, helped trial participants consistently lose at least five to 10 percent of weight when compared to placebo. It also regulates your hunger and fullness, and stabilizes your blood sugar. This can make you feel less cravings and give you better control over your eating habits. However, Saxenda is a prescription injection treatment that requires an initial demonstration by a healthcare professional. Regular injections may be off-putting to some patients. The most common side effects included nausea, diarrhea, and vomiting.
Litramine/XLS-Medical – pros and cons
Litramine is perhaps viewed as a more gentle weight loss treatment as it can be ingested via tea, sachet, or tablet. Side effects from Litramine are mild if they occur at all. Litramine attaches itself to fat in the body and stops the fat being absorbed by the intestines. Clinical trials found it to absorb as much as 27% of dietary fats. It’s not HPFB approved and is more commonly seen outside Canada, but you should be able to get it online.
Victoza – pros and cons
Victoza is effective at helping people with Type 2 diabetes lose weight, as it can help the body control blood sugar levels, and over a course of 56 weeks has been proven to help lose substantial weight. However, Victoza has to be injected daily, which may not be appealing to everyone, and clinical trials on its effectiveness for non-diabetic overweight people are ongoing. It can be prescribed off-label for weight loss. Victoza can cause users to experience side effects of the digestive system. Its use may be unsuitable for patients with a family history of certain cancers.
Ozempic – pros and cons
Ozempic has been found to reduce blood sugar, lower the risk of heart disease and lower cholesterol levels. Clinical trials reported an average loss of 15.3kg after one year. In comparison, patients in the placebo trial lost only 2.6kg. When using Ozempic you can expect a reduction in waist circumference, blood sugar levels and glucose levels. This is a weekly injection treatment - which is much easier than daily Saxenda injections - but some people find injections off-putting full-stop, they aren’t for everyone. Side effects are minimal but include nausea, diarrhea, and vomiting so could be uncomfortable. Is only available on prescription.
Wegovy - pros and cons
Wegovy also boasts the appeal of being a once weekly injection for weight loss. Although, the idea of self administering an injection can put some people off. The clinical trial results for Wegovy show that people lose more weight using semaglutide than when using liraglutide. Most side effects associated with Wegovy are gastrointestinal in nature, although headaches, tiredness and dizziness were also recorded. In most cases the side effects settled down quickly and didn’t stop patients from continuing with their treatment.
Contrave - pros and cons
Contrave will usually make you eat less food, which can cut out overeating habits and reduce your appetite. It’s also very effective. In a trial involving 1742 people, the Contrave group lost 6.1% of their body fat, compared with 1.3% of the placebo group. There is, however, a higher risk of side effects than there is with some other weight loss treatments, and you’ll need a prescription for it before you can buy and take it.