Our average rating based on 3344 reviews.

Starting from CAD438.00
Starting from CAD438.00
Here’s what's included in the price:
Answer a few questions about your health so we can get to know you better.
Free express delivery
Your treatment delivered in secure packaging in 2-3 business days.
We’ll check in with you regularly to see how your treatment is going.

Buy Contrave online

Contrave helps you lose weight by working on the receptors of the brain that control appetite. Together with a healthy diet and exercise, it can help you lose weight.

Get the treatment that works best for you. Talk to us to get personalized treatment suggestions. Order Contrave online and have it delivered to you via subscription.

Starting from CAD438.00
Here’s what's included in the price:
Answer a few questions about your health so we can get to know you better.
Free 24h delivery
Your treatment delivered in secure packaging, the very next day.
We’ll check in with you regularly to see how your treatment is going.
This page was medically reviewed by Ms Laurenmarie Cormier, Nurse Practitioner on August 02, 2022. Next review due on August 01, 2024.

Your partners in health

Mr Paul Zemlak

Pharmacy Registrar and Clinical Prescriber
Mr Paul Zemlak

Registered with ACP (No. 2382)

Meet Paul  

Dr Daniel Atkinson

GP Clinical lead
Dr. Daniel

Registered with GMC (No. 4624794)

Meet Daniel  

Ms Laurenmarie Cormier

Nurse Practitioner
Ms Laurenmarie Cormier

Registered with NPI (No. 1700446366)

Meet Laurenmarie  

Choose how you do healthcare.

We know health, but you know you.
Our experts tell you what’s safe, but you decide what’s best.


Consult on your own time

Answer a few questions and tell us about yourself. Get tailored advice from our clinicians so you can choose better.


Treatments to fit your life

Choose your treatment and how often you have it delivered.

3Your health-continued

Your health, continued

We know things change. It’s the nature of life. We’ll check in regularly to make sure your treatment is still right for you.

4Control at your fingertips

Control at your fingertips

Pause. Change. Skip. Start again. Any time you like.

How are we doing?

Fast, efficient and speedy service. Would recommend!

My second time using your invaluable service. Efficient, effective and value for money. Thank you.

Treated have been a life saver for me. HRT provider 5 *. Promot and efficient personal service. Thank you once again. 😊

Very thorough and very helpful.

The service is on point, very fast and reliable.

Straight forward, sensible and efficient


Our average rating based on 3344 reviews.

Give us the inbox treatment.

We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.

Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.

We’ll deliver to you by

What is Contrave?

Contrave is a weight loss tablet that works in the brain to alter feelings of hunger and how your body spends energy. You’ll start off on a low dose of one tablet per day, and gradually increase this to two tablets twice a day over the first four weeks.

When it’s used alongside a calorie controlled diet and regular exercise, it can be very effective at helping people lose weight. In clinical trials, people taking naltrexone and bupropion had a ‘mean’ (average) weight loss of 5.4% when taking it over 54 weeks, and a mean weight loss of 8.1% when it was combined with behavioral counseling.

Contrave is a medicine that’s only available by prescription, so you’ll need to have a consultation with us about it before you use it.

How does Contrave work?

Contrave weight loss tablets contain naltrexone and bupropion, and these work on the specific area of the brain that controls how much food you eat and how energy is spent. By affecting cravings for food, it makes it less likely you’ll overeat, which can lead to significant weight loss if you make adjustments to your lifestyle too.

The ingredient bupropion is also used in some antidepressant medications, as well as a popular stop smoking treatment called Zyban. So Contrave is quite different to the weight loss tablet Orlistat, which affects how much fat you take up from food.

Is Contrave effective?

Contrave has been shown to work well in clinical trials, and be even more effective when used alongside weight loss management counseling. In a study of people taking it over 56 weeks, there was an average weight loss of 5.4%, and an average weight loss of 8.1% in people who also had behavioral support.

In a combined analysis of studies, up to 42% of people taking Contrave over 56 weeks lost at least 5% of their body weight, and up to 22% lost 10% of their body weight. So it has proven to be effective for a sizable portion of people that take it.

Reference Popover #ref3
Reference Popover #ref1
Reference Popover #ref2

How to take Contrave pills

Read the instructions that come with the medication before you take Contrave. If there’s anything you aren’t sure about, let us know.

  • During week one of treatment, take one tablet once a day in the morning.
  • During week two, take one tablet twice a day, one in the morning and one in the evening
  • During week three, take two tablets in the morning and one in the evening.
  • From week four onwards, take two tablets in the morning and two in the evening.
  • Simply swallow the tablet whole with water, without crushing or breaking them.
  • It’s better to take them with or after a meal and not on an empty stomach.
  • You’ll normally have your weight monitored as the course progresses to make sure it’s working for you.

What should I do if I forget to take Contrave?

If you forget your Contrave dose, don’t worry – just take your next dose as normal and continue the course. Don’t take double the amount at your next dose, because this won’t have any benefit and increases the risk of side effects.

If you’re having trouble remembering to take the medication, you might find it useful to set a daily reminder to take it at specific times, or take it with a specific meal each day.

What should I do if I take too much Contrave?

If you’ve taken too much Contrave, you should seek immediate medical attention. Go to your nearest hospital and take your Contrave packaging with you if possible.

Taking the tablets at the same time each day can help you to remember when to take your tablet and prevent you from taking too much by accident.

Medically reviewed by
Ms Laurenmarie Cormier
Nurse Practitioner
on August 02, 2022.
Meet Laurenmarie  
This page was medically reviewed by Ms Laurenmarie Cormier, Nurse Practitioner on August 02, 2022. Next review due on August 01, 2024.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Contrave: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How safe is Contrave?

Contrave is a safe treatment for the majority of people that use it. In a safety and tolerability review of weight loss medications, the majority of side effects associated with naltrexone and bupropion were transient.

But you should still read the safety info that comes with Contrave before you take it, and report anything unusual to a doctor.

What are the ingredients in Contrave?

There isn’t a non-branded version of Contrave available currently, although the medication is known by different names overseas (in the UK, it’s called Mysimba).

The active components in Contrave are available in other medications. For example, Zyban, a stop smoking treatment, contains bupropion. But this isn’t suitable for use in weight loss.

Can you get side effects with Contrave?

Some people who use Contrave may get side effects, as is the case with any medication. In some cases these might be mild or pass after a short time, but a minority of people may get more serious side effects. If you notice anything that concerns you, it’s important to get medical help right away.

Contrave, Xenical or Saxenda: what’s the difference?

Contrave shares some similarities with other treatments for weight loss. It’s a tablet, like Xenical, but works in a different way to this medication. Xenical, instead, works by preventing the body from digesting fat, which is eliminated without being fully processed by the body.

Like Saxenda, Contrave has an effect on appetite, but the way the medication is administered is quite different (Saxenda is an injection).

So which is better? It depends on a number of things: what you’ve used before, whether it was successful, and to an extent how much weight you need to lose and how quickly you want to lose it. Our clinicians can help you settle on the treatment that works best for you.

Can I only get Contrave by prescription?

Yes, you’ll need a prescription to get Contrave, whether you’re purchasing it online or directly from the pharmacy. This is because its use needs to be monitored by a clinician. For example, if you don’t lose 5% of your weight during the first 16 weeks of treatment, it’s likely you’ll need to try another medication or method of losing weight. Your blood pressure may need to be monitored as well.

Do I need to change my diet and exercise more when taking Contrave?

For any weight loss treatment to work at its best, you’ll need to eat a healthy balanced diet and get regular physical activity when taking it. If you don’t make lifestyle changes but do manage to lose weight with treatment, it’s possible that you’ll regain the weight you lost if you haven’t developed good habits to maintain a healthy weight.

Why should I buy Contrave online with Treated?

We’re tailoring weight loss treatment to your needs. Tell us about your health and we’ll suggest the medications that are best for you and your health. Choose your treatment from there, and how often you’d like us to deliver it to you.

And if you’re unsure about anything, our clinicians are on hand to chat with you. They’ll reach out to you to see how you’re getting on with your medication, and if you’d like us to make any adjustments to it. Change, pause or cancel your subscription at any point.
Want to know something else?

Add a treatment to compare.

Suggest a treatment

If there’s a particular treatment or condition you’re looking for, tell us and we’ll look into it for you.

Tell us about a problem

I accept the terms of use.
We may email you about the problem, but you can opt out of these communications any time you like.

Ask or suggest something.

Submit your question here, or tell us if you’ve found an issue on our site.

We may email you about your query, but you can opt out of these communications any time you like.

Our average rating based on 3344 reviews.

Is this your first time with us?

You can continue as a guest, or sign in with your Treated account if you have one.


Our average rating based on 3344 reviews.


Get the latest health news and articles, sent to your inbox.

By clicking 'Subscribe now' you're agreeing to our Terms.

You’re signed up to our newsletter. Keep an eye on your inbox for our latest update.

We’ll get back to you very soon. We aim to respond to all queries in one working day.

What did you like about it?

What didn't you like about it?

Find a treatment or condition

Choose an option